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Micropatterned Cell-Repellent Interface Using Femtosecond Laser Direct Writing to Engineer Controlled Cell Organization
Yang WG(杨文广)1; Chu HH(褚洪汇)1; Cai SX(蔡树向)1; Liang WF(梁文峰)2; Yu HB(于海波)3; Wang YC(王越超)3; Liu LQ(刘连庆)3
Department机器人学研究室
Source PublicationAdvanced Materials Technologies
ISSN2365-709X
2021
Volume6Issue:7Pages:1-7
Indexed BySCI ; EI
EI Accession number20212310457641
WOS IDWOS:000658021700001
Contribution Rank3
Funding OrganizationNational Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61803323, 61973224] ; Natural Science Foundation of Shandong ProvinceNatural Science Foundation of Shandong Province [ZR2019BF049]
Keywordcell organization cell-repellent interface femtosecond laser direct writing
Abstract

Cell-repellent interfaces have various applications, including microfluidic devices, biosensors, and antibiofouling surfaces. Efficient cell repellency, long-term stability, and ability to fabricate micropatterns with cell repellency are main optimal requirements for cell-repellent interfaces. In this study, a flexible and practical method is proposed to construct a cell-repellent interface and engineer controlled cell organization. Using femtosecond-laser direct writing to pattern surfaces with microcraters, it is shown that micropatterned surfaces with physical and chemical changes have outstanding characteristics of super-hydrophobicity. Furthermore, the cell adhesion is inhibited by these features and arbitrary cell patterns are achieved by selective cell adhesion induced by the distribution of the microcrater structures. These findings suggest a high potential for directing cell organization with desired shapes to analyze the fundamental mechanism of cell adhesion.

Language英语
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sia.cn/handle/173321/29056
Collection机器人学研究室
Corresponding AuthorYang WG(杨文广); Yu HB(于海波); Liu LQ(刘连庆)
Affiliation1.School of Electromechanical and Automotive Engineering, Yantai University, Yantai, 264005, China
2.School of Mechanical Engineering, Shenyang Jianzhu University, Shenyang, 110016, China
3.State Key Laboratory of Robotics, Shenyang Institute of Automation, Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang, 110016, China
Recommended Citation
GB/T 7714
Yang WG,Chu HH,Cai SX,et al. Micropatterned Cell-Repellent Interface Using Femtosecond Laser Direct Writing to Engineer Controlled Cell Organization[J]. Advanced Materials Technologies,2021,6(7):1-7.
APA Yang WG.,Chu HH.,Cai SX.,Liang WF.,Yu HB.,...&Liu LQ.(2021).Micropatterned Cell-Repellent Interface Using Femtosecond Laser Direct Writing to Engineer Controlled Cell Organization.Advanced Materials Technologies,6(7),1-7.
MLA Yang WG,et al."Micropatterned Cell-Repellent Interface Using Femtosecond Laser Direct Writing to Engineer Controlled Cell Organization".Advanced Materials Technologies 6.7(2021):1-7.
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